Avaliação em estudos longitudinais da eficácia do Hipoclorito de sódio e da Clorexidina sobre o Enterococcus faecalis presente em infecções endodônticas - revisão sistemática

by Silva, Julio Almeida

Abstract (Summary)
The efficacy of the sodium hypochlorite and chlorhexidine over theEnterococcus faecalis present in endodontic infections was evaluated inlongitudinal studies through a systematic review. Bibliographic cataloguesources, electronically identified as MEDLINE(, from 1966 until January 1st, andCochrane Library on the same period, were used. On the searching strategy,the following combination of keywords were used ? faecalis and sodiumhypochlorite or faecalis and chlorhexidine or faecalis and root canal infectionsor faecalis and endodontics infections or faecalis and root canal irrigants orfaecalis and irrigant solution or faecalis and endodontics irrigants or faecalisand intracanal irrigant. The studies were selected by two independent reviewersthat determined the inclusion and exclusion criteria. The search presented 229related articles, with 6 of these as literature review articles, 39 articles wererelated with in vivo studies (humans or animals), and 189 included in vitrostudies. From the 39 in vivo studies, 5 studies satisfied the inclusion criteria.The methodological structure of the included studies prohibited the combinationof results. The efficacy of the sodium hypochlorite and chlorhexidine over the E.faecalis was demonstrated in vitro by direct contact test. On the studiesinvolving contaminated dentin, either the sodium hypochlorite or thechlorhexidine were inefficient. On the 5 studies included, from the total of 159teeth with endodontic infections primary or secundary, the E. faecalis wasdetected initially in 16 teeth by PCR and 42 by culture, and after the sanitizationprocess in 11 teeth by PCR and 12 by culture. It was observed the absence oflongitudinal studies in humans about the efficacy of chlorhexidine over the E.faecalis. The sanitization process with the emptying, enlargement and action ofthe sodium hypochlorite reduces the remaining endodontic microbiota, whatcertainly potentiates the action of the intracanal dressing and favors a higherlevel of success of the endodontic treatment.
This document abstract is also available in Portuguese.
Bibliographical Information:

Advisor:Ana Helena Gonçalves de Alencar; João Carlos Gabrielli Biffi; Carlos Estrela

School:Universidade Federal de Uberlândia

School Location:Brazil

Source Type:Master's Thesis

Keywords:E. faecalis Clorexidina Soluçãoirrigadora Sodium hypochlorite Chlorhexidine Irrigantsolution Endodontic infection Systematic review


Date of Publication:07/05/2007

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