Freqüência de sarampo, rubéola, dengue e eritema infeccioso em casos suspeitos de sarampo e rubéola no Estado de Pernambuco, no período de 2001 ? 2004

by Couto Oliveira, Maria José

Abstract (Summary)
Diagnosis of viral enxanthematous diseases presents many failures when based on clinical criteria grounds alone, mainly in countries where measles and rubella are rare. Studies taken in several countries pointed out other determining enxanthematous viral diseases, mistaken as measles and rubella. To verify the frequency of measles and rubella in the state of Pernambuco, in the period from 2001 to 2004, 1,160 serum samples were analyzed in the Central Laboratory of Public Health of Pernambuco (Laboratório Central de Saúde Pública de Pernambuco- LACEN-PE). Immunoenzymatic assays (ELISA) for detection of specific IgM antibodies for each virus were used. A laboratory confirmed diagnosis was achieved in 23% (276/1161) of the cases investigated. From this number, 16,9% (196/1161) were identified as dengue, 3,3% (38/1161) parvovirus B19, 2,8% (32/1161) rubella and 0,9% (10/1161) as measles. All positive cases for measles and 44% of the positive cases for rubella happened probably because of vaccine reaction. This is the first study that makes evident the circulation of B19 parvovirus in Pernambuco, having been observed that 92,1% of the positive cases for it and 90,8% of the positive cases for dengue, having rubella as the diagnosed hypothesis due to the similarity of its symptoms. The high percentage of enxanthematous diseases, without defined ethiology (76,2%), indicated the necessity of implementing a differential diagnosis so that other diseases could be better investigated. This procedure is important to guide the system of epidemiological surveillance that must be implanted after the eradication of measles, besides giving more credibility to the quality and efficacy of the measles-rubella or measles-mumps -rubella vaccine
This document abstract is also available in Portuguese.
Bibliographical Information:

Advisor:Vera Magalhães da Silveira

School:Universidade Federal de Pernambuco

School Location:Brazil

Source Type:Master's Thesis

Keywords:Measles Parvovírus B19 Parvovirus Exanthematous diseases- exanthem Erythema infectiosum


Date of Publication:02/23/2006

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