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A candidate gene study and a full genome screen for male homosexuality [electronic resource] /

by DuPree, Michael G.

Abstract (Summary)
The causes of differences in sexual orientation are poorly understood. Although behavior genetic analyses have found that homosexuality is familial, candidate gene studies reveal no mechanisms that influence the development of the trait. Previous studies of a region of the X chromosome have shown a statistically significant excess of allele sharing at loci on Xq28 between pairs of homosexual brothers, but the locus explains only a portion of variance in the trait. Thus, there are potentially other loci throughout the genome that could influence the development and expression of sexual orientation.
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Advisor:

School:Pennsylvania State University

School Location:USA - Pennsylvania

Source Type:Master's Thesis

Keywords:male homosexuality sexual orientation behavior genetics sex linkage aromatase behavioral mapmaker sibs genome screen analysis affected sibpair candidate gene

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