Use Profile and Monitoring of Adverse Reactions Caused by Herbal Medicines of Live Pharmacy Program in a Health Basic Unit of Fortaleza.

by da Silveira, Patrícia Fernandes

Abstract (Summary)
Through a continuous attendance of ambulatory patients in a Unit of Health of the Family in Fortaleza/Ce, the present work besides describing the use profile to medicines, tells to probable adverse reactions the phytotherapic of the program Alive Pharmacy, wide used as alternative therapeutic in the public net of health, since to the same ones adverse reactions are not usually attributed besides the existence of few published scientific works. To know the profile of use the medicines and adverse reactions the phytotherapic pertaining to the program alive pharmacies of the city hall of Fortaleza and thus to contribute for its safe and efficient use. They participated in the study people that lived in Fortaleza and they were assisted in the UBASF and that they received prescription for the use of such fitoterápicos in the period of April 01 and July 31, 2004, that they agreed in participating. The accompaniment was carried through telephonic linkings and/or responsible return of patient to the pharmacy of the domiciliary rank of health and/or the visits. 112 monitoring had been carried through, 70.50% had been of feminine sex and 29.50% of the masculine sex, with average of age of 27,66 years. Of 299 prescribed medicines 58.53% they had been allopathic and 41.47% phytotherapic; the medicine average for prescription was of 1,11 and the average of phytotherapic was of 1,56. Of patients 89.30% they had used only 1 (one) medicine of the Program Alive Pharmacy and 25% had used the phytotherapic as only option of treatment. The Medicines had been observed 11 notifications of Suspicion of Adverse Reaction, with the envolvement of 7 medicines (3 phytotherapic of the Program Alive Pharmacies and 4 allopathic). Of the 10 patients who had presented RAM, 2 were masculine and 8 feminine, and 2 were children. Digestive system (N=4) followed of the Respiratory System (N=3) and of the Cardiovascular System (N=2) had been the reached therapeutical groups more. How much to the classification: 1 RAM was defined, 4 probable and 3 possible ones; it has led in 5 cases, moderate in 3 and none was considered severe. They had been registered 7 cases of complaint-technique. The number of notified adverse reactions significant was compared with other studies. It is necessary the accomplishment of studies of effectiveness and toxicity of the phytotherapic as well as the popularization of the system of pharmacovigilance of the same ones among professionals of the health so that a safer and rational use.
This document abstract is also available in Portuguese.
Bibliographical Information:

Advisor:Telma Leda Gomes de Lemos; Marta Maria de Fran├ža Fonteles; Mary Anne Medeiros Bandeira

School:Universidade Federal do Ceará

School Location:Brazil

Source Type:Master's Thesis

Keywords:Adverse Reactions Phytotherapic Farmacoepidemiologia


Date of Publication:05/07/2007

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