Studies on the Natural Products of the Formosan Soft Coral Nephthea chabrolii

by Lin, Fang-yi

Investigation on the chemical constituent of a Formosan soft coral Nephthea chabrolii, collected along the coast off Kenting, has led to the isolation of nine marine natural products (1¡V9), including seven new compounds, chabrolosteroids A¡VG (1¡V7), and two known compounds, loliolide (8) and teuhetenone A (9). The structures of 1¡V9 were determined on the basis of spectroscopic analyses, including MS, IR, 1D NMR, and 2D NMR. Cytotoxicities of 1¡V9 against selected cancer cell lines were also measured.