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Speeding changeover in pharmaceutical packaging

by 1980- Shah, Aditya N.

Abstract (Summary)
SHAH, ADITYA NARESH. Speeding Changeover in Pharmaceutical Packaging. (Under the direction of Dr. Wilbur L. Meier Jr.) Pharmaceutical companies increasingly are working to improve productivity and reduce costs in their manufacturing and packaging operations. Expanding markets and innovative marketing strategies have lead to an increased demand in pharmaceutical packaging products. To achieve goals of lower costs, greater flexibility, and increased capacity without substantial investment, pharmaceutical packaging plants are working to streamline their operations by application of lean production and management techniques. This thesis discusses the background of lean production particularly as it relates to the pharmaceutical industry and presents an actual application in a packaging facility of a global pharmaceutical manufacturer. It describes lean production techniques used to reduce cleanup and changeover time in pharmaceutical packaging operations. The changeover reduction process involved evaluating the process with production associates and developing new standard procedures for performing the changeover. It discusses the unique characteristics of a pharmaceutical changeover and highlights techniques used to deal with potential issues within a pharmaceutical operation. The resulting changeover time was reduced by 65 percent resulting in dramatically increased capacity without addition of facilities, capital investments, or negative impact upon product or process quality. Speeding Changeover in Pharmaceutical Packaging By Aditya N. Shah A thesis submitted to the Graduate Faculty of North Carolina State University in partial fulfillment of the requirements for the Degree of Master of Science in
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School:North Carolina State University

School Location:USA - North Carolina

Source Type:Master's Thesis

Keywords:north carolina state university

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