Respuesta serológica y seguimiento de los pacientes con infección por el virus de la inmunodeficiencia humana vacunados frente a streptococcus pneumoniae

by Len Abad, Òscar

In summary, the conclusions are: 1. In general, the specific IgG response to pneumococcal vaccine is lower in patients with HIV infection than in healthy subjects. However, 33% patients are able to mount an adequate response comparable to that of healthy subjects with independence to the CD4 lymphocyte count. 2. In the 5 year follow-up there has been no episodes of pneumococcal disease. Because of the high incidence rate of pneumococcal disease and the lack of side effects derived from the vaccination, we recommend it to the HIV infected population. 3. Finally, we have demonstrated that the specific IgG antibody titre return to baseline levels before 3 years, even in patients with a normal response, suggesting that in case of revaccination, this would have to be planned during this period.