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Neurologists’ Practices and Attitudes Regarding Genetic Testing for Alzheimer Disease

by Poskochil, Jamie

Abstract (Summary)
Purpose: The purpose of this study was to describe the current practices and attitudes of neurologists regarding genetic testing for Alzheimer disease. Methods: A questionnaire was mailed to 2274 neurologists in the United States. Results: Ninety-three percent of respondents reported familiarity with and 36% reported having ordered apolipoprotein E testing, while 51% reported familiarity with and only 8.8% reported having ordered presenilin 1, presenilin 2, or amyloid precursor protein testing. In five different patient scenarios neurologists indicated a strong correlation in their decision to offer apolipoprotein E and autosomal dominant early-onset genetic testing. Neurologists who were familiar with testing cited different motivations for offering genetic testing than those who were not familiar. Conclusion: Our results indicate that neurologists may not distinguish between the vastly different uses of these genetic tests. Developing a relationship between neurologists and genetic professionals could benefit both groups and could foster comprehensive patient care.
Bibliographical Information:

Advisor:

School:University of Cincinnati

School Location:USA - Ohio

Source Type:Master's Thesis

Keywords:genetic counseling testing alzheimer disease neurologists genetics

ISBN:

Date of Publication:01/01/2005

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