Optic Disc Changes after Pan-Retinal Photocoagulation for Proliferative Diabetic Retinopathy
Kappa statistics indicated strong intra- and inter-observer consistency of observations for both cup-to-disc ratio and optic color (0.61 and 0.79, respectively). A paired t-test showed that change in optic pallor was significant after treatment with PRP (p = 0.0004). However, when comparing to the change in the control group using a Students t-test, no significance was found (p = 0.387). No significant change was found in cup-to-disc ratio.
A few conclusions can be made from this study. First, the newly created grading scheme for optic pallor is both reliable and reproducible. While PRP treatment may cause an increase in optic pallor, the change is not significantly different than that seen with merely the passage of time. Lastly, cup-to-disc ratio was not significantly affected by PRP treatment. Further studies may be indicated to elaborate on the effect of PRP on the optic nerve.
Advisor:Ron A. Adelman, MD
School Location:USA - Connecticut
Source Type:Master's Thesis
Keywords:therapy retina diabetic retinopathy light coagulation ophthalmology
Date of Publication:03/25/2008