Hapsite (R) gas chromatography - mass spectrometry with solid phase microextraction /

by Kan, WaiKwong.

Title of Thesis: “HAPSITE® Gas Chromatography - Mass Spectrometry with Solid Phase Microextraction” Author: CAPT Waikwong Kan Master of Science in Public Health Thesis Directed by: CDR Gary L. Hook Assistant Professor Department of Preventive Medicine and Biometrics Rapid air sampling can be accomplished with solid phase microextraction (SPME) to avoid the difficulties of pumps and wet chemistry. Gas chromatography with mass spectrometry (GC/MS) is the gold standard for identifying volatile and semivolatile chemicals. Combining SPME with a portable HAPSITE GC/MS may allow rapid chemical identification outside of a laboratory. Six chemicals at six concentrations were tested using four sample introduction methods. The four methods included the HAPSITE loop, the HAPSITE with tri-bed concentrator, the HAPSITE with SPME and a field portable GC/MS with SPME. The SPME fiber used was Polydimethylsiloxane (PDMS). The HAPSITE with tri-bed concentrator achieved the lowest detection limits. The