Estudios moleculares en Bartonella bacilliformis para el control de la enfermedad de Carrión
Abstract (Summary)Carrion’s Disease is caused by Bartonella bacilliformis bacterium, and is transmitted by several species of the vector insect of the Lutzomyia genus. Animal reservoir is not known; seemingly the man is the only one. This disease is endemic in Peru and is actually considered as re-emergent because their geographical distribution comes expanding. Thus it is important to study its molecular markers for established diagnosis methods that are quick and effective. On the treatment aspect, it is necessary to evaluate the antibiotics used against the disease. On the therapeutic topic, more research is required regarding the antigenic proteins from this bacterium; this fact is important to develop future vaccine against this disease or diagnostic assay for their detection in the laboratory or to improve the sensitivity and specificity of the current methods. IalB and FlaA are interesting proteins due to than they are involved in the bacterial invasion to the human erythrocyte.
Source Type:Master's Thesis
Keywords:verruga peruana bartonella
Date of Publication:01/01/2008