Error-Tolerant Coding and the Genetic Code
The main advance in this thesis is a set of methods for calculating the primordial evolutionary pressures that shaped the genetic code. These pressures are due to genetic errors, and hence the statistical properties of the errors and of the genome are imprinted in the statistical properties of the code. Thus, by studying the code it is possible to reconstruct, to some extent, the primordial error rates and the composition of the primordial genome. In this way, I find evidence that the fixation of the genetic code occurred in organisms which were not thermophiles.
School:University of Waterloo
School Location:Canada - Ontario
Source Type:Master's Thesis
Keywords:mathematics genetic code evolution mathematical model error minimization biology rna world coding information theory
Date of Publication:01/01/2006