Determination to the humoral immune response after suplementation with Probiotic in nelore bovine
The effect of a probiotic on the immune response of cattle immunized with one dose of rabies vaccine was evaluated in this study. The Nelore bovines (N=75) were divided randomly into 5 groups: four groups fed with a diet supplemented with the 2, 3, 4 and 8 g the probiotic (Proenzime®)/bovine/day, groups G2, G3, G4 and G8, respectively, for 60 days. The 5th group was used as control. All the animals were immunized with a single dose of rabies vaccine on the first day of the experiment (day 0). The antibody titers were measured on days 0, 30 and 60 by RFFIT test. The results show the significant interaction was found between the probiotic level and vaccination time. There was also a significant difference among rabies titers in groups Gc, G2, G3, G4 and G8 on both days 30 and 60. In group G4, titers of rabies antibody in cattle decreased significantly on day 60. A significant difference (plt;0.05) between the frequency of immunized animals in the control group and the other treatments was found on both days 30 and 60. On day 60, the control group did not differ from G2. However, no significant difference (plt;0.05) was found among the treatments which were supplemented with probiotic. In addition, no significant difference (plt;0.05) between the frequency of immunized animals on days 30 and 60 was found in control (Gc) or any other treatment (G2, G3, G4 or G8). In conclusion, the probiotic (Proenzime®) increase the humoral immune response of bovine immunized with rabies vaccine.
Advisor:Renata Navarro Cassu; Luiz Fernando Coelho da Cunha Filho; Paulo Eduardo Pardo
School:Universidade do Oeste Paulista
Source Type:Master's Thesis
Keywords:Cattle - Probiotic
Date of Publication:08/27/2008