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DATA MINING OF PEPTIDE MS/MS SPECTRA TO ELUCIDATE GAS-PHASE PEPTIDE DISSOCIATION MECHANISMS AND IMPROVE PROTEIN IDENTIFICATION

by Huang, Yingying.

Abstract (Summary)
Mining of datasets obtained from proteomics experiments was performed to investigate the dissociation pathways of protonated peptides activated in the gas phase under low energy collision-induced dissociation (CID). Intensity patterns in ion trap tandem mass spectra were exploited and different statistical approaches were employed to elucidate the dissociation mechanisms.
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School:The University of Arizona

School Location:USA - Arizona

Source Type:Master's Thesis

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