Body Mass Index as a predictor of morbidity and mortality following lung transplantation
Abstract (Summary)Limited data are available on the relationship between Body Mass Index (BMI) and rnorbidity and mortality in lclng transplant populations. The objective of this study was to measure the association between post-transplant morbidity and mortality and preoperative BMI in end stage lung disease (ESLD). Dependent measures included Mortality at 90 days and 1 year post-transplantation; length of time in the Intensive Care Unit; length of time in the hospital; and. number of rejection episodes. Patients were grouped by BMI categories: 47 kglm2; 17 to c20 kg/m2; 20 to 25 kg/rn2;>25 to 27 kg/mz; and. >27kglmz. The results indicated that patients with a pre-transplant BMI cl7 kg/rn2 showed a trend to increased rnortality following transplantation (p=0.085). Patient with a BMI >27 kg/m2 had a significant increase in mortality (p=0.003). In conclusion. a pre-transplant BMI > 27kg/m2 was found to be a predictor of morbidity and mortality in ESLD patients post-transplantation.
Source Type:Master's Thesis
Date of Publication:01/01/1999